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Publication Profiles

Perspectives on preparing for long-acting injectable treatment for HIV among consumer, clinical and nonclinical stakeholders: A qualitative study exploring the anticipated challenges and opportunities for implementation in Los Angeles County

Citation

Jolayemi O, Bogart LM, Storholm ED, et al. Perspectives on preparing for long-acting injectable treatment for HIV among consumer, clinical and nonclinical stakeholders: A qualitative study exploring the anticipated challenges and opportunities for implementation in Los Angeles County. PLoS One. 2022;17(2):e0262926. doi:10.1371/journal.pone.0262926

Implementation stage:

Implementation

Implementation outcomes reported:

Not applicable

Continuum target addressed:

Viral suppression, ART adherence

Geography:

Los Angeles County-CA

Study Participant Classification:

Community member(s), Implementer(s)

Plain Language Objectives

Before long-acting injectable HIV treatment was widely available, the researchers asked patients and other stakeholders in Los Angeles County what might make it easier or harder to introduce. They wanted to identify concerns and practical implementation needs.

Plain Language Abstract

Long-acting injectable antiretroviral therapy offers an alternative to daily HIV pills, but successful rollout requires attention to patient and health-system needs. In February 2020, researchers interviewed 18 consumers and 23 clinical or nonclinical stakeholders in Los Angeles County. Participants expected injections could reduce pill burden, adherence anxiety, and stigma. They also anticipated missed injection visits, discomfort, medication resistance, eligibility requirements, and cost as barriers. Medical mistrust and external policies could affect access. Within organizations, respondents raised concerns about payment authorization, staffing, medication purchasing and storage, and readiness to adopt a new treatment. Participants were generally optimistic and described knowledge and positive beliefs as supporting acceptability, while acknowledging that providers might hesitate when clinics lacked resources. This qualitative preimplementation study captured anticipated opportunities and challenges before routine rollout. It did not measure actual adoption, adherence, viral suppression, or effectiveness after implementation. The findings reflect the views of the 41 people interviewed and were intended to guide local planning and scale-up.

Key Takeaways

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