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Publication Profiles

Perspectives on and preferences for on-demand and long-acting PrEP among sexual and gender minority adolescents assigned male at birth

Citation

Macapagal K, Nery-Hurwit M, Matson M, Crosby S, Greene GJ. Perspectives on and preferences for on-demand and long-acting PrEP among sexual and gender minority adolescents assigned male at birth. Sex Res Social Policy. 2021;18(1):39-53. doi:10.1007/s13178-020-00441-1

Implementation stage:

Pre-Implementation

Implementation outcomes reported:

AcceptabilityLinkage to preventative care,PrEP initation,PrEP adherence,PrEP persistence

Continuum target addressed:

Linkage to preventative care, PrEP initiation, PrEP adherence, PrEP persistence

Geography:

Non-priority jurisdiction

Study Participant Classification:

Recipients of care

Plain Language Objectives

The researchers asked sexual and gender minority adolescents assigned male at birth about daily and longer-acting HIV-prevention options. They wanted to learn which methods adolescents preferred and how convenience, access, and parental involvement affected their choices.

Plain Language Abstract

Daily oral pre-exposure prophylaxis, or PrEP, is available to adolescents, but taking a pill every day and obtaining confidential care can be difficult. Researchers conducted online surveys and focus groups with 59 sexual and gender minority adolescents assigned male at birth between November 2018 and February 2019. Participants reported attraction to or sex with male partners and discussed daily pills, on-demand pills, injections, implants, and condoms. Implants and condoms received the highest overall ratings, and participants preferred implants among the biomedical options. Convenience, how long a method lasted, and ease of access strongly shaped preferences. Participants viewed parents as a potential barrier across PrEP methods because parents often control access to health care. The findings show interest in long-acting options alongside broader developmental and legal barriers. Because the study measured preferences rather than actual use, it cannot show which methods adolescents would adopt or continue. The qualitative findings and survey ratings reflect this sample, and the study did not test an intervention.

Key Takeaways

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